Table 3.

Subsequent chronic diseases in men and women.

	Cancer survivors		Non-cancer patients		P-value	HR2		(95% CI)
	N	Inc1	N	Inc1
Ten most common subsequent diseases in cancer patients
Diabetes mellitus†	133	13.46	589	14.79	0.31	0.91	0.75	1.09
Venous thrombosis
Baseline—2 years	45	9.27	40	2.11	0.00	4.20	2.74	6.44
2 years—end of follow-up†	20	3.10	58	2.11	0.15	1.45	0.87	2.41
Osteoporosis	99	8.93	354	7.90	0.15	1.18	0.94	1.47
Chronic obstructive pulmonary disease	95	8.81	378	8.56	0.97	1.00	0.80	1.25
Heart failureδ	94	8.31	380	8.28	0.80	0.97	0.77	1.22
Stroke/cerebrovascular accident	92	8.27	435	9.81	0.08	0.82	0.65	1.03
Dementiaβ	83	7.16	417	8.93	0.07	0.81	0.64	1.02
Ischemic heart disease without anginaβ	71	6.76	308	7.17	0.50	0.92	0.71	1.19
Ischemic heart disease with angina	65	6.29	294	7.03	0.36	0.88	0.67	1.15
Osteoarthrosis hip	66	6.05	268	6.11	0.95	1.01	0.77	1.32
Significant differences between cancer and non-cancer patients3
Hypertension with organ damage	41	3.67	250	5.55	0.01	0.66	0.48	0.92
Lipid disorders
Baseline—2 years	16	3.66	129	7.62	0.01	0.49	0.29	0.82
2 years—end of follow-up	31	5.27	171	7.08	0.16	0.76	0.52	1.11
Benign prostatic hypertrophy	27	5.05	223	10.87	0.00	0.46	0.31	0.69

¹Inc: incidence per 1000 person years at risk.

²HR: hazard ratio adjusted for sex, age, cardiovascular diseases, respiratory diseases, and diabetes.

³Please see Table 3 in the Supplementary Material on the journal website for all other diseases.

^†Adjusted for age as time-varying coefficient.

^δAdjusted for sex and age as time-varying coefficient.

^βAdjusted for cardiovascular diseases as time-varying coefficient.