Table 2.
Prognostic biomarkers for early stage breast cancer
| Biomarker | Name | Tissue source | Technique | Reference |
|---|---|---|---|---|
| 21-gene Recurrence Score | Oncotype Dx | FFPE | Q-RT-PCR | [131] |
| Amsterdam 70-gene assay | MammaPrint | Fresh or frozen | RNA microarray | [180] |
| 97-gene grade signature | MapQuantDx | Fresh or frozen | RNA microarray | [167] |
| Rotterdam 76-gene signature | Veridex | Fresh or frozen | RNA microarray | [186] |
| Proliferation Signature | Fresh or frozen | RNA microarray | [42] | |
| Stem Cell/Invasiveness Gene Signature | Fresh or frozen | RNA microarray | [96] | |
| Wound Response Signature | Fresh or frozen | RNA microarray | [29] | |
| HoxB l31/L17BR | Theros | FFPE | Q-RT-PCR | [105] |
FFPE: Formalin Fixed Paraffin Embedded.