Table 1.
Sample characteristics (Baltimore metropolitan area, 2000–2004)
| Variable | Women without hot flashes | Women with hot flashes | p value |
|---|---|---|---|
|
| |||
| n (%)a | n (%)a | ||
| Total sample size | 267 | 372 | |
| Age group (years) | |||
| 45 to 49 | 194 (72.7) | 219 (58.9) | <0.01 |
| 50 to 54 | 73 (27.3) | 153 (41.1) | |
| Race | |||
| Caucasian | 230 (86.1) | 302 (81.2) | 0.01 |
| African American | 28 (10.5) | 66 (17.7) | |
| Other | 8 (2.9) | 3 (0.8) | |
| Body mass index (kg/m2) | <0.01 | ||
| <25.0 | 127 (47.6) | 146 (39.2) | |
| 25.0 to 29.9 | 81 (30.3) | 94 (25.3) | |
| ≥30.0 | 59 (22.1) | 131 (35.2) | |
| Cigarette smoking | 0.01 | ||
| Current | 16 (6.0) | 42 (11.3) | |
| Former | 94(35.2) | 153 (41.1) | |
| Never | 157 (58.8) | 176 (47.3) | |
| AHR (rs2066853) | 0.06 | ||
| +/+ (GG) | 190 (71.4) | 244 (65.8) | |
| +/− (GA) | 69 (25.9) | 103 (27.7) | |
| −/− (AA) | 7 (2.7) | 24 (6.5) | |
| AHRR (rs2292596) | 0.99 | ||
| +/+ (CC) | 111 (41.7) | 157 (42.3) | |
| +/− (CG) | 144 (54.1) | 199 (53.6) | |
| −/− (GG) | 11 (4.2) | 15 (4.1) | |
| ARNT (rs2228099) | 0.82 | ||
| +/+ (GG) | 84 (31.6) | 126 (34.0) | |
| +/− (GC) | 136 (51.1) | 182 (49.0) | |
| −/− (CC) | 46 (17.3) | 63 (17.0) | |
| CYP1B1 (rs1800440) | 0.19 | ||
| +/+ (AA) | 186 (69.9) | 251 (67.5) | |
| +/− (AG) | 74 (27.8) | 102 (27.4) | |
| −/− (GG) | 6 (2.3) | 19 (5.1) | |
| CYP1B1 (rs1056836) | 0.30 | ||
| +/+ (CC) | 77 (28.9) | 87 (23.5) | |
| +/− (CG) | 122 (45.9) | 180 (48.7) | |
| −/− (GG) | 67 (25.2) | 103 (27.8) | |
a
Due to missing information, some columns do not add up to the total n listed, and percentages do not add up to 100