Table 2. Descriptive statistics for both cell proliferation assays and supernatant immunoglobulin levels for AU-ASD and Typically Developing children.

Treatment groups were either unstimulated (No-Stim) or stimulated with B cell specific antigens. Staphylococcus aureus C protein, Pokeweed mitogen, and T cell conditioned medium were included in the 3-Stim treatment group while the 4-Stim treatment group included all reagents in 3-Stim in as well as CpG.

Assay	Treatment	Diagnosis	N	Median	ta	p-value
Cell Proliferation (Total cells per well)	No-Stim B cell	AU-ASD	29	19,087	27,420	0.491
		TD	28	23,000	13,704
	No-Stim IgM+ B cell	AU-ASD	29	16,677	15,153	0.446
		TD	28	17,055	13,923
	No-Stim Proliferating B cell	AU-ASD	29	1,770	2,140	0.761
		TD	28	1,689	3,107
	No-Stim IgG+ B cell	AU-ASD	29	3,665	3,283	0.858
		TD	28	3,555	4,017
	3-Stim B cell	AU-ASD	29	27,635	25,868	0.997
		TD	28	30,670	19,950
	3-Stim IgM+ B cell	AU-ASD	29	17,892	15,920	0.672
		TD	28	21,319	17,566
	3-Stim Proliferating B cell	AU-ASD	29	3,191	5,525	0.349
		TD	28	3,810	7,298
	3-Stim IgG+ B cell	AU-ASD	29	3,775	4,364	0.213
		TD	28	5,455	4,727
	4-Stim B cell	AU-ASD	29	72,349	41,279	0.386
		TD	28	67,418	43,618
	4-Stim IgM+ B cell	AU-ASD	29	53,859	41,742	0.348
		TD	28	46,376	42,361
	4-Stim Proliferating B cell	AU-ASD	29	53,648	48,912	0.201
		TD	28	50,518	40,102
	4-Stim IgG+ B cell	AU-ASD	29	10,329	7,997	0.99
		TD	28	10,205	10,876
Supernatants (ng/ml Ig)	No-Stim IgG	AU-ASD	35	56.89	26.28	0.971
		TD	29	51.76	27.95
	No-Stim IgM	AU-ASD	30	5.09	7.83	0.254
		TD	28	5.02	3.12
	3-Stim IgG	AU-ASD	35	36.62	24.44	0.594
		TD	30	32.65	20.69
	3-Stim IgM	AU-ASD	30	7.49	6.84	0.321
		TD	28	7.85	5.35
	4-Stim IgG	AU-ASD	35	40.28	19.6	0.133
		TD	30	32.96	19.52
	4-Stim IgM	AU-ASD	30	22.75	36.92	0.512
		TD	28	23.77	29.19