Table 1.

Patient Demographic Pre-operative and Operative Characteristics

	Neoadjuvant Chemotherapy (N=2006)		No Neoadjuvant Chemotherapy (N=42527)		P value
Variable	N	%	N	%
Demographics
Age in years [mean (SD)]	52.1 (12.0)		59.63 (13.1)		<0.0001
Race/ethnicity
White	1362	67.9	30663	72.1	<0.0001
Black	256	12.8	4314	10.1
Other	224	11.2	3874	9.1
Missing	164	8.2	3676	8.6
Preoperative health and co-morbidities
Current smoker	323	16.1	6114	14.4	0.032
Alcohol use (>2 drinks per day)	13	0.7	636	1.5	0.002
Functional status: partial/fully dependent	22	1.1	582	1.4	0.304
Body Mass Index classification
Normal weight	596	29.7	13842	32.6	0.001
Underweight	41	2.0	998	2.4
Overweight/Obese	1367	68.2	27536	64.8
Diabetes Mellitus	111	5.5	3726	8.8	<0.0001
Chronic Obstructive Pulmonary Disease	24	1.2	1133	2.7	<0.0001
Previous cardiac surgery	13	0.7	768	1.8	0.0001
Congestive heart failure	8	0.4	77	0.2	0.029
Hypertension (requiring medication)	602	30.0	18209	42.8	<0.0001
History of transient ischemic attack	15	0.8	773	1.8	0.0004
Steroid use	79	3.9	515	1.2	<0.0001
Bleeding disorder	55	2.7	675	1.6	<0.0001
Open or infected wound	31	1.6	272	0.6	<0.0001
Preoperative Lab Values
White Blood Cell count >11 or <4.5	650	32.4	4387	10.3	<0.0001
Missing	141	7.0	7513	17.7
Hematocrit <38	1473	73.4	11128	26.2	<0.0001
Missing	115	5.7	6707	15.8
Platelet count <150 or >400	226	11.3	2258	5.3	<0.0001
Missing	146	7.3	7565	17.8
Operative Variables
American Society of Anesthesiologists class
No disturbance	48	2.4	3029	7.1	<0.0001
Mild disturbance	1234	61.5	26898	63.3
Severe disturbance	706	35.2	12057	28.4
Life-threatening disturbance	16	0.8	499	1.2
Blood transfusion	15	0.8	112	0.3	0.003
Wound Class
Clean	1930	96.2	41574	97.8	<0.0001
Clean-contaminated/dirty/infected	76	3.8	953	2.2
Type of Surgery
Breast Conserving surgery	220	11.0	13571	31.9	<0.0001
Mastectomy	1406	70.1	20482	48.2
Mastectomy with Immediate Reconstruction	380	18.9	8474	19.9
Axillary lymph node dissection	1720	85.7	20477	48.2	<0.0001
Sentinel lymph node biopsy	286	14.3	22050	51.9