Table 3.
Multivariable model of factors associated with wound complications in patients undergoing breast cancer surgery
| Factor | N (%)N = 44533 | Adjusted Odds Ratio | 95% Confidence Interval | P value |
|---|---|---|---|---|
| Neoadjuvant chemotherapy | 2006 (4.5%) | 1.00 | 0.77 – 1.31 | 0.973 |
| Age | 1.00 | 0.99–1.00 | 0.252 | |
| Race | ||||
| White | 32025 (71.9%) | 1.00 | Reference | |
| Black | 4570 (10.3%) | 0.82 | 0.65–0.98 | 0.431 |
| Other | 4098 (9.2%) | 0.80 | 0.65–0.98 | 0.229 |
| Smoker | 6437 (14.5%) | 1.56 | 1.35–1.80 | <0.0001 |
| Partial/fully dependent | 604 (1.4%) | 2.02 | 1.43–2.88 | <0.0001 |
| Overweight/obese | 28903 (64.9%) | 2.16 | 1.87–2.50 | <0.0001 |
| Diabetes mellitus | 3837 (8.6%) | 1.57 | 1.33–1.85 | <0.0001 |
| Hypertension | 18811 (42.2%) | 1.25 | 1.10–1.43 | 0.001 |
| Type of Breast Surgery | ||||
| Breast conserving surgery | 13791 (31.0%) | 1.00 | Reference | |
| Mastectomy | 21888 (49.2%) | 1.82 | 1.54–2.16 | 0.034 |
| Mastectomy + reconstruction | 8854 (19.9%) | 2.51 | 2.09–3.02 | <0.0001 |
| Axillary lymph node dissection* | 22197 (49.8%) | 1.00 | 0.88–1.14 | 0.945 |
*
Analysis performed using sentinel lymph node biopsy as the reference