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. Author manuscript; available in PMC: 2013 Sep 1.
Published in final edited form as: Cancer Res. 2012 Jul 2;72(17):4383–4393. doi: 10.1158/0008-5472.CAN-11-3893

Figure 5. RUNX1 re-expression can inhibit anchorage-independent growth in an esophageal adenocarcinoma cell model.

Figure 5

a) Focal deletion of locus 21q22.12 containing RUNX1 in esophageal adenocarcinomas, OE33 (EA), and A549 (non-small cell lung cancer) cell lines. b) OE33 and A549 cell lines were stably transduced with retrovirus containing RUNX1. Immunoblotting confirmed positive expression of RUNX1. c) Soft-agar colony formation for OE33 and A549 cells with ectopic GFP or RUNX1 expression. Representative images of colony formation at 6.3X magnification. Quantitation of three independent experiments; error bars represent S.E.M. **, P < 0.005; n.s., not significant.