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. Author manuscript; available in PMC: 2013 Sep 1.

Published in final edited form as: Nanomedicine. 2012 May 26;8S1:S77–S82. doi: 10.1016/j.nano.2012.05.004

Fig. 1 — CPT in micelles reduces cellular content within the CIA joints. Representative joint sections of (A) empty SSM-VIP-injected mice, (B) CPT-SSM-VIP treated mice; (left to right) CD3+, CD3−, lysozyme+, lysozyme− staining. Bars represent 10 µm. (C) Average pooled immunohistochemical scores of cellular infiltration and distribution in joints of CIA mice on () Day 38 and (■) Day 60. Results are expressed as mean ± S.E.M. (6 mice/group). *, †p< 0.05 versus SSM-VIP and SSM, respectively.

Inline graphic — CPT in micelles reduces cellular content within the CIA joints. Representative joint sections of (A) empty SSM-VIP-injected mice, (B) CPT-SSM-VIP treated mice; (left to right) CD3+, CD3−, lysozyme+, lysozyme− staining. Bars represent 10 µm. (C) Average pooled immunohistochemical scores of cellular infiltration and distribution in joints of CIA mice on () Day 38 and (■) Day 60. Results are expressed as mean ± S.E.M. (6 mice/group). *, †p< 0.05 versus SSM-VIP and SSM, respectively.