Figure 4. Effect of OVX and bisphosphonate treatment on biochemical markers of bone turnover in wild type (WT) and Gja1 conditional knockout (cKO) mice.
(A) Serum C-terminal telopeptides of type I collagen (CTX); and (B) serum osteocalcin in the different genotypes and treated groups (n=5–9), (See Fig. 2 for abbreviations). a, p< 0.05 vs WT; b, p< 0.05 vs Sham; c, p<0.05 vs OVX+Veh, 2-way ANOVA, and post-hoc multiple t-test (Holm-Sidak).