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. Author manuscript; available in PMC: 2013 Oct 1.
Published in final edited form as: Bone. 2012 Jun 29;51(4):787–794. doi: 10.1016/j.bone.2012.06.018

Figure 5. Effect of OVX and bisphosphonate treatment on cortical bone turnover in wild type (WT) and Gja1 conditional knockout (cKO) mice.

Figure 5

(A) Osteoclast number and (B) osteoclast surface as percentage of endocortical surface area, assessed by TRAPC+ staining of femur section in the different genotypes and treated groups (See Fig. 2 for abbreviations). (C) Periosteal bone formation rate (BFR); (D) periosteal mineral appostion rate (MAR); (E) endosteal BFR; and (F) endosteal MAR in the different genotypes and treated groups at the end of the study (n=4). a, p< 0.05 vs WT, b, p< 0.05 vs Sham; c, p<0.05 vs OVX+Veh, 2-way ANOVA, and post-hoc multiple t-test (Holm-Sidak).