Table 2.

Efficacy outcomes for patients on treatment for at least 12 months

Outcome measure	Baseline		At 12 months/during 12-month treatment period
	n	Value	n	Value
Annualized relapse ratea	826	Median 2.0 (0–14)	825	Median 0.0 (0–4)b
		Mean 2.01 (1.92–2.11)		Mean 0.25 (0.21–0.29)
Percentage of patients with at least one relapsea	826	733 (88.7%)	825	168 (20.4%)
Basal EDSS score	839	Median 3.50 (0–8.5)	839	3.00 (0–7.5)c
		Mean 3.71 (3.60–3.82)		Mean 3.37 (3.25–3.49)
Patients with Gd-enhancing lesions at baseline	563	289 (51.3%)	563	33 (5.9%)

Results presented as median (range), mean (95% confidence interval), or absolute number (%)

EDSS Expanded Disability Status Scale

^aIn the year prior to baseline

^b p < 0.001 versus baseline (Wilcoxon test)

^c p < 0.001 versus baseline (McNemar test)