Fig. 8.

Effects of pre-administered L-AsA and vitamin E on changes in brain AsA (A), GSH (B), and vitamin E (C) contents in rats with 6 h of WIRS. Fasted rats with and without 6 h of WIRS were orally administered with L-AsA (1.5 mmol/kg) or vitamin E (0.5 mmol/kg) at 0.5 h after the onset of stress. Brain AsA, GSH, and vitamin E were assayed as described in Materials and Methods. Each value is a mean ± SD (n = 5 for unstressed groups; n = 8 for stressed groups). *Significantly different from control rats without WIRS and any administration, p<0.05; ^#Significantly different from rats with WIRS alone, p<0.05.