Table 3.
p Value | Adjusted OR* | 95% CI | |
---|---|---|---|
Sexes of subjects included | |||
Females only | Reference | ||
Males only | 0.18 | 0.9 | 0.8 to 1.0 |
Females and males | 0.08 | 1.1 | 1.0 to 1.2 |
Age groups included | |||
Adults | Reference | ||
Adults and children | 0.18 | 1.0 | 0.9 to 1.0 |
Children only | 0.46 | 1.0 | 0.9 to 1.1 |
Year of registration | |||
1999 | Reference | ||
2000 | <0.001 | 11.5 | 8.8 to 15.0 |
2001 | <0.001 | 8.9 | 6.8 to 11.6 |
2002 | <0.001 | 9.1 | 7.0 to 11.9 |
2003 | <0.001 | 11.9 | 9.2 to 15.4 |
2004 | <0.001 | 11.8 | 9.1 to 15.2 |
2005 | <0.001 | 5.5 | 4.3 to 7.0 |
2006 | <0.001 | 15.5 | 12.2 to 19.7 |
2007 | <0.001 | 15.6 | 12.3 to 19.8 |
2008 | <0.001 | 19.9 | 15.7 to 25.2 |
2009 | <0.001 | 31.4 | 24.8 to 39.9 |
2010 | <0.001 | 42.3 | 33.3 to 53.8 |
2011 | <0.001 | 46.8 | 36.4 to 60.3 |
Study phase | |||
Phase I | Reference | ||
Phase II | <0.001 | 1.2 | 1.2 to 1.3 |
Phase III | <0.001 | 1.2 | 1.1 to 1.3 |
Phase IV | <0.001 | 0.8 | 0.7 to 0.9 |
Source of funding | |||
Industry only | Reference | ||
Non-industry only | <0.001 | 0.6 | 0.6 to 0.7 |
Blended | <0.001 | 0.8 | 0.8 to 0.9 |
*Logistic regression model included the following covariates: sex composition of subjects; age groups; year of registration; study phase; and source of funding.