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(a) MS3D model of the full-length Ψ-RNA generated using footprinting and crosslinking data.65 High-resolution structures for the discrete stem-loop domains SL1 (red), SL2 (green), SL3 (blue) and SL4(yellow) were employed as building blocks. Linker regions (orange) were generated de novo. (b) Details of H-bonding and interactions between SL1 and SL4 domains in the observed GNRA-tetraloop interaction. Adapted with permission from reference 65.
