FIG. 2.

Histological analyses of ectopic endochondral bone formation in unaltered male and unaltered female hosts. (a–d) 21 days post implantation of MDSC-B4 (e–h) 42 days post implantation. Both hematoxylin and eosin (H&E) and green fluorescent protein (GFP) immunostaining are shown. “new” indicates new bone tissue formed, while “cart” indicates cartilage formed during the endochondral ossification process. (i) cartilage fraction (%) of new tissue, *indicates different from unaltered male at same time (p<0.05) (j) bone fraction (%) of new tissue, *indicates different from unaltered male at same time (p<0.05). Arrows indicate GFP positive (brown) cells. All images 200×. Color images available online at www.liebertpub.com/tea