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. Author manuscript; available in PMC: 2013 Jul 1.
Published in final edited form as: Allergy. 2012 May 14;67(7):904–910. doi: 10.1111/j.1398-9995.2012.02841.x

Figure 4.

Figure 4

CpG methylation at the IL-4 and IFN-γ promoters in grandoffspring (F2) following sensitization of female mice (F0) to Aspergillus fumigatus. Methylation data are presented as mean ± standard error. (A) IL-4 CpG−408: Methylation in grandoffspring (F2) of mice dosed early with A. fumigatus was lower than in grandoffspring of mice dosed late (P < 0.0005). (B) IL-4 CpG−393: Methylation in grandoffspring (F2) of mice dosed early with A. fumigatus was lower than in grandoffspring of mice dosed late (P < 0.0005). (C) IFN-γ CpG−205: Methylation in grandoffspring (F2) of mice dosed early with A. fumigatus was lower than in grandoffspring of mice dosed late (P < 0.0005). (D) IFN-γ CpG−190: Methylation in grandoffspring (F2) of mice dosed early with A. fumigatus was lower than in grandoffspring of mice dosed late (P < 0.0005).