Table 1.
Identification of top biological functions altered in RanBPM shRNA cells using IPA.
| Diseases and Disorders | ||
|---|---|---|
| Name | p-value | # of molecules |
| Cancer | 2.43E-04 - 3.79E-02 | 57 |
| Reproductive System and Disease | 2.43E-04 - 2.86E-02 | 19 |
| Gastrointestinal Disease | 5.43E-04 - 3.79E-02 | 16 |
| Organismal Injury and Abnormalities | 5.43E-04 - 3.79E-02 | 10 |
| Inflammatory Response | 1.34E-03 - 3.79E-02 | 19 |
|
| ||
| Molecular and Cellular Functions | ||
|
| ||
| Name | p-value | # of molecules |
| Cellular Function and Maintenance | 2.60E-04 - 3.79E-02 | 22 |
| Cell Morphology | 2.73E-04 - 3.14E-02 | 12 |
| Cellular Assembly and Organization | 2.73E-04 - 3.79E-02 | 10 |
| Lipid Metabolism | 9.00E-04 - 3.79E-02 | 10 |
| Small Molecule Biochemistry | 9.00E-04 - 3.79E-02 | 20 |
|
| ||
| Physiological System Development and Function | ||
|
| ||
| Name | p-value | # of molecules |
| Tissue Development | 7.03E-04 - 3.79E-02 | 42 |
| Hematological System Development and Function | 2.60E-04 - 3.79E-02 | 22 |
| Organ Morphology | 9.00E-04 - 3.79E-02 | 10 |
| Reproductive System Development and Function | 9.00E-04 - 3.79E-02 | 9 |
| Connective Tissue Development and Function | 1.02E-03 - 3.79E-02 | 23 |
Top biological function in each category is bolded.