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. Author manuscript; available in PMC: 2012 Sep 4.
Published in final edited form as: Front Biosci. 2012 Jan 1;17:1120–1139. doi: 10.2741/3977

Figure 1.

Figure 1

RUNX1 isoforms and genomic locus. (A) The RUNX1 genomic locus on chromosome 21 is shown with the location of the proximal and distal promotors and exons based on the National Center for Biotechnology Information Nucleotide database. (B) The three main transcriptional isoform of RUNX1 are shown. RUNX1a is consists of exons 4a through 8. RUNX1b consists of exons 4a through 10, but excludes exon 8. RUNX1c includes exons 1 through 3 and exons 4b through 10, but also excludes exon 8. (C) The three main RUNX1 isoforms are shown with the Runt homology domain shaded.