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P-glycoprotein (P-gp) activity in brain endothelial cell (BEC) cultures derived from gestational day (GD) 40, 50, 65 and postnatal day (PND) 14 male guinea pigs (N = 4). P-gp activity is displayed as percent change from GD40 BECs (zero line). P-gp function was calculated over relative cell count. Values displayed as mean ± S.E.M. A significant difference from GD40 indicated by (*) P<0.05; (***) P<0.001.
