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Effect of resveratrol on pro-inflammatory cytokines. Quantitative real-time PCR was used to measure IL-1β, IL-6, and TNF-α mRNA expression in cecal tissue. The values for each specimen were normalized to the GAPDH mRNA level of that specimen. Results are shown relative to the mean for vehicle treated HSA-injected animals. Statistical significance was achieved for all of these cytokines at the 100 mg/kg/d dose. (Results shown are means; n=4– 6/group; error bars reflect SEM.)
