Table 4.
Summary statistics for the urinary concentrations (in ng/mL) of DEHP metabolites (non creatinine-adjusted) in men from both studies separately and combined (N=850)
Study | Geometric Mean | Selected Percentiles | P valuef | |||||
---|---|---|---|---|---|---|---|---|
LODa | % > LODb | 10th | 50th | 90th | ||||
Variables | ||||||||
MEHP (ng/mL) | ||||||||
SFF | 3.7 | 1.2 | 77 | 0.85 | 3.2 | 17.8 | ||
MGH | 8.2 | 1.0 | 83 | 1.0 | 7.9 | 64.3 | ||
TOTAL | 4.9 | 80 | 0.9 | 4.4 | 39.2 | < 0.001 | ||
MEHHP (ng/mL) | ||||||||
SFF | 23.3 | 0.7 | 99 | 4.6 | 23.7 | 104 | ||
MGHc | 55.6 | 1.3 | 100 | 13.2 | 47.0 | 272 | ||
TOTALd | 27.6 | 99.5 | 5.4 | 25.3 | 170 | < 0.001 | ||
MEOHP (ng/mL) | ||||||||
SFF | 12.9 | 0.7 | 97 | 2.7 | 12.9 | 57.4 | ||
MGHc | 36.2 | 1.1 | 99 | 8.4 | 32.2 | 193 | ||
TOTALd | 16.1 | 98 | 3.2 | 15.4 | 110 | < 0.001 | ||
MEP (ng/mL) | ||||||||
SFF | 206 | 0.8 | 100 | 31.8 | 205 | 1358 | ||
MGH | 179 | 1.1 | 100 | 30.2 | 153 | 1376 | ||
TOTAL | 173 | 100 | 23.6 | 170 | 1259 | < 0.001 | ||
MBP (ng/mL) | ||||||||
SFF | 19.2 | 0.6 | 98 | 4.0 | 24.5 | 65.3 | ||
MGH | 17.1 | 0.8 | 97 | 5.1 | 17.7 | 50.8 | ||
TOTAL | 16.3 | 97.5 | 3.4 | 18.8 | 58.2 | < 0.001 | ||
MBzP (ng/mL) | ||||||||
SFF | 11.2 | 0.3 | 98 | 2.1 | 12.5 | 49.8 | ||
MGH | 7.7 | 0.7 | 97 | 2.3 | 8.2 | 24.9 | ||
TOTAL | 8.4 | 97.5 | 1.6 | 9.8 | 41.2 | < 0.001 | ||
MEHP%e | ||||||||
SFF | 9.4 | 3.9 | 10.1 | 18.8 | ||||
MGHc | 9.4 | 3.5 | 10.3 | 24.3 | ||||
TOTALd | 9.4 | 3.7 | 10.1 | 21.6 | 0.59 |
Limit of detection (LOD) in ng/mL for each phthalate metabolite.
Percentage of samples above the LOD for each phthalate metabolite
N= 221
N= 646
To calculate MEHP%, we transformed MEHP, MEHHP and MEOHP concentrations to nanomoles per milliliter, divided MEHP levels by the sum of concentrations of MEHP, MEHHP and MEOHP, and then multiplied by 100
Mann-Whitney U Test