Table 5.
Correlation coefficients for reproductive hormones and DEHP metabolites1 concentrations in men (bivariate analysis) (n=850)
| Study | MEHP | MEHHP | MEOHP | ||||
|---|---|---|---|---|---|---|---|
| R | 95% CI | R | 95% CI | R | 95% CI | ||
| FSH | |||||||
| SFF | .003 | (−.09, .10) | −.01 | (−.11, .09) | −.01 | (−.11, .09) | |
| MGH | .04 | (−.05, .14) | −.03 | (−.16, .10) | −.04 | (−.17, .09) | |
| TOTAL | .16 | (.09, .23)d | .10 | (.03, .18)d | .14 | (.06, .22)d | |
| LH | |||||||
| SFF | −.01 | (−.11, .09) | −.02 | (−.12, .08) | −.03 | (−.13, .07) | |
| MGH | −.04 | (−.14, .05) | −.01 | (−.15, .12) | −.01 | (−.14, .13) | |
| TOTAL | .14 | (.07, .21)d | .12 | (.04, .20)d | .16 | (.08, .24)d | |
| T | |||||||
| SFF | −.07 | (−.17, .03) | −.09 | (−.19, .01) | −.10 | (−.20, −.001)c | |
| MGH | −.15 | (−.24, −.05)c | −.13 | (−.25, .001) | −.12 | (−.25, .01) | |
| TOTAL | −.16 | (−.23,−.10)d | −.15 | (−.23, −.08)d | −.17 | (−.25, −.09)d | |
| E2 | |||||||
| SFFa | −.06 | (−.16, .04) | −.02 | (−.12, .08) | −.02 | (−.12, .08) | |
| MGH | −.12 | (−.22, −.03)c | −.07 | (−.20, .06) | −.06 | (−.19, .08) | |
| TOTALb | −.04 | (−.10, .03) | −.02 | (−.10, .06) | −.01 | (−.09, .07) | |
| SHBG | |||||||
| SFF | .06 | (−.04, .16) | −.03 | (−.13, .07) | −.03 | (−.13, .07) | |
| MGH | −.05 | (−.15, .05) | .03 | (−.10, .16) | .04 | (−.09, .17) | |
| TOTAL | −.01 | (−.08, .05) | −.02 | (−.10, .06) | −.02 | (−.10, .06) | |
| FAI | |||||||
| SFF | −.15 | (−.25, −.06)d | −.06 | (−.16, .04) | −.07 | (−.17, .03) | |
| MGH | −.08 | (−.18, .01) | −.17 | (−.29, −.04)d | −.17 | (−.29, −.04)d | |
| TOTAL | −.15 | (−.22,−.09)d | −.14 | (−.21, −.06)d | −.16 | (−.23, −.08)d | |
| FT | |||||||
| SFF | −.12 | (−.22, −.03)d | −.09 | (−.19, .01) | −.10 | (−.20, −.001)c | |
| MGH | −.16 | (−.25, −.06)d | −.19 | (−.31, −.06)d | −.19 | (−.31, −.05)d | |
| TOTAL | −.19 | (−.26,−.13)d | −.17 | (−.25, −.10)d | −.19 | (−.27, −.12)d | |
| T/E2 | |||||||
| SFFa | −.002 | (−.10, .10) | −.05 | (−.15, .05) | −.06 | (−.16, .04) | |
| MGH | .03 | (−.07, .13) | −.01 | (−.14, .12) | −.02 | (−.15, .11) | |
| TOTALb | −.07 | (−.14, .−.01)c | −.09 | (−.17, −.01)c | −.11 | (−.19, −.03)d | |
1
non-creatinine-adjusted/non-SG-adjusted
a
N= 405 for E2
b
N= 830 for E2
c
P value≤.05
d
P value≤.01
R= correlation coefficient
CI= confidence interval
Log-transformations of phthalate metabolites and men sex hormones, except for E2 were used