. 2012 Aug 1;189(5):2584–2596. doi: 10.4049/jimmunol.1200999

Table I. Number of NKT cells, macrophages, and DCs and mRNA levels of cytokines and chemokines in kidneys of WT→WT, S1pr3^−/−→WT, and WT→S1pr3^−/− BM chimeras after ischemia and 24 h reperfusion.

	WT→WT	S1pr3^−/−→WT	WT→S1pr3^−/−
Immune cells^a
NKT cells (×10⁴)	4.0 ± 0.84*	4.1 ± 1.53	3.8 ± 1.37
Macrophages (×10⁵)	2.6 ± 0.49*	0.9 ± 0.31	3.1 ± 0.51*
CD11c cells (×10⁵)	1.1 ± 0.27	1.7 ± 0.52	0.8 ± 0.24
mRNA levels^b
TNF-α	3.82 ± 0.92**	1.56 ± 0.56	4.22 ± 0.91*
IL-12p40	2.21 ± 0.06*	1.51 ± 0.16	2.79 ± 1.06
IL-1β	10.75 ± 3.35*	1.94 ± 0.58	12.46 ± 3.90**
IL-6	23.63 ± 6.46***	1.31 ± 0.35	12.47 ± 2.83*
CXCL1	31.26 ± 9.47**	1.23 ± 0.24	12.76 ± 2.23**
CXCL2	34.67 ± 12.15*	1.77 ± 0.66	30.68 ± 10.96**
CXCL5	21.92 ± 6.69**	4.69 ± 1.23	11.62 ± 3.61**

^{^a}

For immune cells, the total numbers of NKT (CD45⁺7-AAD⁻CD19⁻TCRβ^lowCd1d^tet) cells, macrophages (CD45⁺7-AAD⁻CD11b⁺F4/80^low), and CD11c (CD45⁺7-AAD⁻CD11c⁺) cells, expressed as fold ratios relative to respective sham-operated mice and as determined by flow cytometry, are shown (n = 3–6/group). Data are means ± SEM. *p < 0.05 relative to sham-operated mice.

^{^b}

mRNA expression levels shown are relative to GAPDH and are expressed as fold ratios relative to respective sham-operated mice (n = 4–9/group). Data are means ± SEM. *p < 0.05, **p < 0.01, ***p < 0.001 relative to sham-operated mice.

Table I. Number of NKT cells, macrophages, and DCs and mRNA levels of cytokines and chemokines in kidneys of WT→WT, S1pr3−/−→WT, and WT→S1pr3−/− BM chimeras after ischemia and 24 h reperfusion.

Table I. Number of NKT cells, macrophages, and DCs and mRNA levels of cytokines and chemokines in kidneys of WT→WT, S1pr3^−/−→WT, and WT→S1pr3^−/− BM chimeras after ischemia and 24 h reperfusion.