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. Author manuscript; available in PMC: 2012 Sep 4.
Published in final edited form as: Cell Metab. 2006 Apr;3(4):237–245. doi: 10.1016/j.cmet.2006.02.012

Figure 7.

Figure 7

Starvation induces pumping in a muscarinic signaling-dependent manner

A) Starvation induced pumping in a muscarinic signaling-dependent manner. Pumping rates increased for first 2 hr in the absence of food. Two mutants defective in muscarinic signaling showed altered pumping rates compared to wild-type. gpb-2 mutants, which have upregulated muscarinic signaling, showed a higher pumping rate, and gar-3 mutants, which have downregulated muscarinic signaling, showed a lower pumping rate than wild-type.

B) A suggested pathway for function of the muscarinic receptor → MAPK pathway in starvation.