Table 2.

Pedagogical attributes (scale of biological organization, genomic level of analysis, and bioinformatic skills taught) of I³Us developed in this project and disseminated on the project's website

		Questions asked at the level of							Analysis			Bioinformatics skills/tools
I³U^a	Focal taxa	Evolution	Behavior	Physiology	Morphology	Cell	Molecular	Biochemistry	Functional	Comparative	Metagenomic	Species-specific DNA database	Multi-species genome browser	Protein modeling	BLAST/alignment	Phylogenetics	Programming
A	Brassica				√		√			√					√
B	Human	√					√			√
C	Wood frog	√	√				√			√
D	Fish/vertebrates	√					√	√	√	√					√
E	Fish/vertebrates	√			√		√			√					√	√
F	Xenopus	√					√		√				√		√	√
G	Pea/various	√		√			√		√			√
H	Eubacteria			√			√	√			√				√	√
I	Mouse		√		√	√			√			√	√		√
J	Worm		√							√		√			√	√
K	Dog	√					√			√				√	√	√	√
L	Various	√		√		√	√			√					√	√
M	Various	√					√			√		√			√		√
N	N/A						√			√					√		√

^aLetters denote I³U units as follows: A: Reconstructing the Evolution of Cauliflower and Broccoli; B: Human Single Nucleotide Polymorphism Determination; C: Local Population Structure and Behavior of the Wood Frog Rana sylvatica; D: Comparison of Protein Sequences: BLAST Searching and Phylogenetic Tree Construction; E: Phylogenetic Analysis of Bony Fishes: Morphological and mtDNA Sequence Comparisons; F: Molecular Evolution of Gene Families; G: Exploring the Chamaecrista fasciculata Gene Space; H: Metagenomic Analysis of Winogradsky Columns; I: Behavior, Neuroanatomy, Genomics: What Can We Learn from Mouse Mutants?; J: Expression of Gerontogenes in Neurons: A Comparative Genomic Approach to Studying the Role of the Nervous System in Lifespan/Aging; K: Comparison of a Highly Polymorphic Olfactory Receptor Gene Subfamily in Genetically Diverse Dog Breeds; L: Integrative Activities to Study the Evolution of Nervous System Function; M: Modeling Molecular Evolution; N: Constructing and Using a PAM-Style Scoring Matrix.