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GM-CSF and IL-6 modulate BM-derived MDSC glucose metabolism. (A) Glucose concentration in the supernatant. (B) Cell specific concentrations in G-6-P (squares) and F-6-P (triangles). (C) Cell specific PEP concentration. (D) Lactate-to-glucose yield. BM cells and BM-derived MDSCs were extracted using cold methanol and organic acids were analyzed using a UPLC-MS/MS system.
