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. 2012 Sep 4;7(9):e44498. doi: 10.1371/journal.pone.0044498

Figure 5. 4b treatment does not affect histone acetylation in mouse brain.

Figure 5

(A) Representative immunoblot showing histone acetylation in mouse brain in response to 4b treatment. Mice treated with SAHA were used as a positive control (B). Acetylation at specific lysine residues on histone 3 (H3K4, H3K9, H3K14) and Histone 4 (H4K5) as well as global acetylation of H3 (Ac-H3) and H4 (Ac-H4) were studied using specific antibodies. Acetylation level was normalized to H3 and H4 expression level. (C) and (D) Quantification of (A) and (B) respectively. **P<0.01, *P<0.05 versus vehicle (veh). n = four per treatment. Error bars indicate SEM.