Table 2. Comparison of number of contacts made by each ligand with monomer A and B of wtTTR.
TTR residues | C1 | C2 | C3 | C6 | C7 |
Lys15A | 10 | 2 | |||
Leu17A | 3 | 2 | 9 | 1 | 3 |
Thr106A | 1 | ||||
Ala108A | 2 | 6 | 6 | 5 | 6 |
Ala109A | 2 | 8 | 4 | ||
Leu110A | 6 | 6 | 2 | 6 | |
Ser117A | 6 | 10 | 7 | 10 | 7 |
Thr118A | 2 | 4 | 3 | 4 | 4 |
Thr119A | 3 | 5 | 3 | 4 | 3 |
Val121A | 3 | ||||
Lys15B | 5 | 4 | 7 | ||
Leu17B | 7 | 6 | 7 | 2 | |
Thr106B | 1 | ||||
Ala108B | 2 | 2 | 3 | 2 | 5 |
Ala109B | 4 | 1 | |||
Leu110B | 4 | 8 | 3 | 5 | |
Ser117B | 1 | 5 | 7 | 5 | 8 |
Thr118B | 2 | 3 | 4 | ||
Thr119B | 4 | 3 | 2 | 1 | 3 |