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. 2012 Sep 4;7(9):e44569. doi: 10.1371/journal.pone.0044569

Table 3. Multivariate associations between NT-proBNP and cognitive test scores.

MHVS g BVFT LM FACES ln(TMT-B) DSC LNS MR
Model 1a β −0.26 −0.09 0.02 −0.49 −0.31 0.03 −0.96 −0.10 −0.35
95% CI −0.54, 0.01 −0.13, –0.03** −0.65, 0.69 −0.91, −0.06* −0.71, 0.10 0.01, 0.05* −1.71, −0.20** −0.25, 0.04 −0.62, −0.08**
Model 2b β −0.05 0.28 −0.36 −0.20 0.02 −0.69 −0.04 −0.25
95% CI −0.09, 0.00* −0.33, −0.89 −0.75, 0.04 −0.59, 0.19 0.00, 0.04* −1.38, 0.00* −0.18, 0.90 −0.50, −0.01*
Model 3c β −0.04 0.38 −0.48 −0.15 0.02 −0.26 −0.04 −0.23
95% CI −0.08, 0.01 −0.26, 1.01 −0.89, −0.07* −0.56, 0.26 0.00, 0.04 −0.98, 0.46 −0.17, 0.10 −0.48, 0.02
Model 4d β −0.02 0.18 −0.57 −0.01 0.02 0.19 −0.01 −0.15
95% CI −0.07, 0.03 −0.52, 0.87 −1.02, −0.11* −0.46, 0.44 −0.01, 0.04 −0.60, 0.98 −0.16, 0.15 −0.43, 0.13
Model 5e β −0.02 0.16 −0.56 −0.03 0.01 0.26 0.01 −0.14
95% CI −0.06, 0.03 −0.56, 0.88 −1.03, −0.08* −0.50, 0.44 −0.01, 0.04 −0.54, 1.07 −0.15, 0.16 −0.42, 0.15

The β scores are regression coefficients.

a

adjusted for age and sex.

b

adjusted for +MHVS.

c

adjusted for + smoking status, blood pressure, BMI, HbA1c, cholesterol, mode of treatment.

d

adjusted for + MI, angina, stroke, ABI.

e

adjusted for + ln(HADS depression).

*

significant at 0.05 level.

**

significant at 0.01 level.