Table 1.
QOL scores (mean differences) of individuals with and without each Axis I disorder at mean age 33 (N=640)
| Axis I Disorders | No. (%) of participants |
Physical Health |
Social Relationship |
Psychological Well-being |
Role Function |
Environmental Context |
|---|---|---|---|---|---|---|
| No Axis I disorder Mean (SD) |
457 |
70.0(17.3) |
79.1(10.5) |
83.2(11.7) |
65.1(15.2) |
76.7(8.9) |
| Alcohol use | 72(11.2) | −5.3* | −4.1** | −6.3*** | −3.8 | −4.5*** |
| Drug use | 24(3.8) | −2.8 | −3.2 | −1.4 | −2.5 | −3.2 |
| MDD | 78(12.2) | −13.9*** | −5.2*** | −13.3*** | −3.2 | −5.0*** |
| Dysthymia | 14(2.2) | −13.3** | −16.5*** | −21.0*** | 0.1 | −3.8 |
| Bipolar | 10(1.6) | −15.8**) | −18.4*** | −22.1*** | −1.3 | −11.5*** |
| Panic | 29(4.5) | −16.3*** | −7.4** | −11.6*** | 2.3 | −4.4* |
| GAD | 16(2.5) | −15.4** | −11.3*** | −13.8*** | −2.4 | −6.3** |
| OCD | 26(4.1) | −12.6** | −8.7*** | −13.4*** | −3.6 | −5.3** |
| Agoraphobia | 28(4.4) | −12.0** | −10.8*** | −13.7*** | −1.6 | −4.9** |
| Social phobia | 24(3.8) | −4.9 | −7.4** | −8.6** | 3.9 | −3.5 |
| PTSD | 17(2.7) | −21.5** | −8.8** | −20.8*** | −0.2 | −2.4 |
| Any Axis I disorder | 183(28.6) | −8.8*** | −4.0*** | −8.2*** | −3.2* | −4.0*** |
Separate regression analyses for each QOL domain score in patients with each disorder compared with the 457 participants with no Axis I disorders, adjusted for all demographic variables, any physical illness and personality disorder.
*
p<0.05;
**
p <0.01;
***
p <0.001