Table 3.
Application of CKiD prediction equations to 1/3 validation set of 322 person-visits of the Chronic Kidney Disease in Children (CKiD) study with iGFR 44.4 ± 17.2 ml/min per 1.73m2
| Model | eGFR | Bias† | 95% LOA‡ | Correlation | % of eGFR within 30% of iGFR | % of eGFR within 10% of iGFR |
|---|---|---|---|---|---|---|
| Univariate | ||||||
| I: ht/SCr | 43.4 ± 13.5 | -1.0 | -19.2, 17.1 | 0.84 | 80.4% | 36.0% |
| II: Cystatin C | 44.7 ± 15.2 | 0.3 | -17.5, 18.1 | 0.85 | 82.6% | 37.6% |
| III: BUN | 43.0 ± 11.5 | -1.4 | -25.3, 22.5 | 0.71 | 65.5% | 27.3% |
| Bivariate | ||||||
| I & II | 44.1 ± 14.6 | -0.3 | -15.4, 14.7 | 0.90 | 88.8% | 38.2% |
| I & III | 43.4 ± 13.7 | -1.0 | -17.5, 15.5 | 0.87 | 83.9% | 35.1% |
| II & III | 44.6 ± 15.3 | 0.1 | -16.7, 17.0 | 0.87 | 82.3% | 35.4% |
| Multivariate: | ||||||
| I&II&III | 44.1 ± 14.7 | -0.4 | -14.9, 14.2 | 0.90 | 89.1% | 41.9% |
| Final | 44.2 ± 14.9 | -0.2 | -13.4, 13.0 | 0.92 | 91.0% | 45.0% |
eGFR (ml/min per 1.73m2); LOA, Limits of Agreement.
†
bias = average of 322 (eGFR – iGFR) values, in ml/min per 1.73 m2
‡
95% LOA = bias ± 1.96 ·standard deviation of (eGFR – iGFR)