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. Author manuscript; available in PMC: 2013 Sep 1.
Published in final edited form as: J Neurochem. 2012 Jul 11;122(6):1145–1154. doi: 10.1111/j.1471-4159.2012.07839.x

Fig. 4. Isolation of non-inactivating and inactivating voltage-gated K+ currents in small DRG neurons.

Fig. 4

(A) Representative traces of whole outward currents from three separated cells evoked by voltage steps (shown below the traces) from a 2-second pre-potential of −60 mV (top) or −100 mV (middle and bottom). (B) Same activation steps as in A, but preceded by a 2-second pre-pulse to −10 mV to remove inactivating current component, which isolated non-inactivating K+ currents (IK currents). (C) Subtraction of non-inactivating currents from whole-currents revealed two types of inactivating K+ currents (IA currents): fast inactivating (IAf) (top) and slow inactivating (IAs) currents (middle) in two separate DRG neurons. The bottom panel shows the mixture of both IAf and IAs currents in a single DRG neuron.