Table 1.
Model | Equilibria | Kd values |
---|---|---|
1 | 50 μM5 | |
103μM3 | ||
2 | 5 μM2 | |
5 μM | ||
35 μM3 | ||
3 | 3.5 μM | |
1 μM | ||
1 μM | ||
25 μM3 |
Dissociation constants (Kd) for each assembly step were obtained by modeling according to Eq. 9. Model 1 is judged to be inconsistent with experiment, whereas Models 2 and 3 provide good fits to the data.