Table 2.
Comparison of age- and cause-specific mortality fractions (CSMF) using the InterVA-3 and InterVA-4 models on 1,000 randomly selected VA records from a previous analysis of data in Agincourt HDSS, South Africa (12)
| Cause-specific mortality fractions by age group (%) | |||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
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| All-age | ≤ 28 days | 1–11 months | 1–4 years | 5–14 years | 15–49 years | 50–64 years | 65+ years | ||||||||||
| n=1000 | n=15 | n=50 | n=79 | n=35 | n=437 | n=139 | n=245 | ||||||||||
| InterVA-4 cause (WHO 2012 categories*) | v4 | v3 | v4 | v3 | v4 | v3 | v4 | v3 | v4 | v3 | v4 | v3 | v4 | v3 | v4 | v3 | InterVA-3 cause |
| 01.02 ARI, including pneumonia | 5 | 4 | 35 | 25 | 11 | 6 | 3 | 1 | 1 | 5 | 5 | 4 | 6 | Pneumonia/sepsis | |||
| 01.03 HIV/AIDS related death | 19 | 17 | 16 | 22 | 39 | 49 | 15 | 6 | 25 | 25 | 16 | 8 | 4 | 0 | HIV/AIDS-related death | ||
| 01.04 diarrhoeal diseases | 3 | 2 | 10 | 21 | 13 | 5 | 4 | 3 | 0 | 2 | 1 | 1 | Diarrhoea | ||||
| 01.05 malaria | 1 | 0 | 5 | 4 | 4 | 1 | 0 | 2 | 0 | Malaria | |||||||
| 01.07 meningitis | 0 | 2 | 2 | 5 | 1 | 3 | 15 | 1 | 1 | 2 | Meningitis | ||||||
| 01.08 tetanus | 0 | 0 | 1 | Tetanus | |||||||||||||
| 01.09 pulmonary tuberculosis | 19 | 20 | 1 | 5 | 4 | 10 | 5 | 25 | 26 | 21 | 20 | 19 | 22 | Pulmonary tuberculosis | |||
| 01.10 pertussis | 0 | 2 | 0 | ||||||||||||||
| 01.99 other infectious diseases | 3 | 2 | 8 | 3 | 4 | 4 | |||||||||||
| 02.01 oral neoplasms | 0 | 1 | 0 | 2 | 0 | 3 | Malignancy | ||||||||||
| 02.02 digestive neoplasms | 4 | 2 | 9 | 8 | |||||||||||||
| 02.03 respiratory neoplasms | 3 | 2 | 4 | 5 | |||||||||||||
| 02.05, 02.06 reproductive neoplasms | 2 | 1 | 0 | 5 | |||||||||||||
| 02.99 other neoplasms | 1 | 1 | 0 | 2 | |||||||||||||
| 03.02 severe malnutrition | 0 | 0 | 3 | 0 | 0 | 1 | Malnutrition | ||||||||||
| 03.03 diabetes mellitus | 2 | 3 | 2 | 1 | 5 | 1 | 1 | 2 | 4 | 5 | 5 | Diabetes | |||||
| 04.01 acute cardiac disease | 1 | 0 | 1 | 0 | 1 | 1 | 2 | 0 | Acute cardiac death | ||||||||
| 04.02 stroke | 1 | 1 | 0 | 2 | 1 | 1 | 2 | Stroke | |||||||||
| 04.03 sickle cell with crisis | 1 | 1 | 11 | 0 | Haemoglobinopathy | ||||||||||||
| 04.99 other cardiac disease | 2 | 4 | 3 | 4 | 1 | 2 | 2 | 8 | 4 | 9 | Chronic cardiac death | ||||||
| 05.01 COPD | 1 | 2 | 0 | 1 | 1 | 5 | 3 | 3 | Chronic respiratory disease | ||||||||
| 05.02 asthma | 1 | 3 | 1 | 1 | |||||||||||||
| 06.01 acute abdomen | 2 | 1 | 2 | 2 | 2 | 4 | |||||||||||
| 06.02 liver cirrhosis | 0 | 4 | 1 | 0 | 2 | 1 | 6 | 1 | 8 | Liver disease | |||||||
| 07.01 renal failure | 1 | 1 | 2 | 1 | 0 | 2 | 2 | 1 | 4 | Kidney disease | |||||||
| 08.01 epilepsy | 1 | 0 | 1 | 4 | 1 | 0 | 1 | Disease of nervous system | |||||||||
| 98 other NCD | 0 | 0 | 0 | 0 | 0 | ||||||||||||
| 09.01 ectopic pregnancy | 0 | 0 | 0 | 1 | Maternal-related death | ||||||||||||
| 09.02 abortion-related death | 0 | 0 | |||||||||||||||
| 09.06 pregnancy-related sepsis | 0 | 0 | |||||||||||||||
| 09.07 anaemia of pregnancy | 0 | 0 | |||||||||||||||
| 10.01 prematurity | 0 | 0 | 24 | 13 | 2 | Pre-term/small baby | |||||||||||
| 10.02 birth asphyxia | 0 | 1 | 19 | 43 | Perinatal asphyxia | ||||||||||||
| 10.03 neonatal pneumonia | 1 | 0 | 40 | 26 | Pneumonia/sepsis | ||||||||||||
| 10.06 congenital malformation | 0 | 4 | |||||||||||||||
| 10.99 other neonatal conditions | 0 | 5 | |||||||||||||||
| 12.01 road traffic accident | 3 | 4 | 0 | 1 | 4 | 6 | 10 | 5 | 6 | 2 | 2 | 1 | 1 | Transport-related accident | |||
| 12.03 accidental fall | 0 | 1 | 3 | ||||||||||||||
| 12.04 accidental drowning | 0 | 0 | 1 | 1 | 6 | 5 | Accidental drowning | ||||||||||
| 12.05 smoke, fire and flames | 0 | 1 | 1 | ||||||||||||||
| 12.07 accidental poisoning | 1 | 1 | 1 | 3 | 0 | 1 | 1 | 0 | Accidental poisoning | ||||||||
| 12.08 intentional self-harm | 1 | 1 | 3 | 3 | 2 | 1 | 1 | 1 | 1 | Suicide | |||||||
| 12.09 assault | 4 | 3 | 2 | 7 | 6 | 4 | 4 | 0 | 0 | Homicide | |||||||
| 12.99 other external causes | 1 | 0 | 1 | 3 | 1 | 4 | 1 | 1 | 0 | 2 | 2 | 0 | Other fatal accident | ||||
| 99 indeterminate | 17 | 29 | 12 | 18 | 18 | 23 | 11 | 22 | 23 | 36 | 12 | 26 | 15 | 31 | 19 | 31 | Indeterminate |
| Total over all causes | 100 | 100 | 100 | 100 | 100 | 100 | 100 | 100 | 100 | 100 | 100 | 100 | 100 | 100 | 100 | 100 | |
*
These demonstration data included 44/62 of the cause of death categories in the 2012 WHO VA instrument and InterVA-4.
CSMFs are rounded to nearest 1%, 0 representing a finite value<0.5%.