Fig. 1.

Pseudorabies virus (PRV) induces pelvic pain in female mice. Pelvic allodynia was quantified with von Frey filaments. Responses to pelvic stimulus are shown for C57BL/6J mice infected with inactivated (sham) PRV (A) or active PRV (B) (n = 5 mice/group). Data represent mean ± SE response to 10 successive applications for each fiber. ANOVA analysis shows a significant increase in responses at all filaments tested in PRV-infected mice at postinfection days (PID) 2, 3, and 4 relative to baseline (P < 0.05).