Fig. 1.
Effects of dopamine and its antagonists on flow-induced changes in fluid (A), sodium (B), bicarbonate (C), and chloride (D) absorption (Jv, JNa, JHCO3, and JCl) in mouse proximal tubules. Jv, JNa, JHCO3, and JCl were measured at low and high perfusion rates in the absence and presence of dopamine (10−5 M), SCH23390 (SCH; DA1 inhibitor, 10−5 M) and sulpiride (Sul; DA2 inhibitor, 10−5 M), *P < 0.05, compared with low flow rates in the same group; †P < 0.05, compared with the control at a similar flow rate.