Fig. 3.
Effects of dopamine, 8-bromo-cAMP (8-Br-cAMP), and PKA inhibitor on flow-induced changes in fluid (A), sodium (B), bicarbonate (C), and chloride (D) absorption (Jv, JNa, JHCO3, and JCl) in proximal tubules. Jv, JNa, JHCO3, and JCl were measured at low and high perfusion rates in absence and presence of dopamine (10−5 M), 8-Br-cAMP (10−4 M), and PKA inhibitor H89 (10−6 M) respectively. *P < 0.05, compared with low flow rates in the same group; †P < 0.05, compared with the control at a similar flow rate.