Table III. Receiver operating characteristics from IHC scores of the three proteins in distinguishing NBE from preneoplastic lesions (SM, AH, and CIS) individually and as a panel. PPV, positive predict value; NPV, negative predict value; AUC, area under the curve.

Proteins	Sensitivity	Specificity	PPV	NPV	AUC
HSPB1	0.85	0.65	0.88	0.50	0.79
GSTP1	0.80	0.63	0.87	0.55	0.78
CKB	0.74	0.61	0.88	0.43	0.75
A panel of three proteins	0.96	0.92	0.97	0.86	0.98