Table V. Receiver operating characteristics from IHC scores of the three proteins in distinguishing preneoplastic lesions (SM, AH and CIS) from invasive LSCC individually and as a panel.
Proteins | Sensitivity | Specificity | PPV | NPV | AUC |
---|---|---|---|---|---|
HSPB1 | 0.68 | 0.79 | 0.86 | 0.55 | 0.80 |
GSTP1 | 0.77 | 0.67 | 0.84 | 0.51 | 0.77 |
CKB | 0.68 | 0.80 | 0.89 | 0.52 | 0.81 |
A panel of three proteins | 0.92 | 0.91 | 0.92 | 0.83 | 0.96 |