Table V. Receiver operating characteristics from IHC scores of the three proteins in distinguishing preneoplastic lesions (SM, AH and CIS) from invasive LSCC individually and as a panel.

Proteins	Sensitivity	Specificity	PPV	NPV	AUC
HSPB1	0.68	0.79	0.86	0.55	0.80
GSTP1	0.77	0.67	0.84	0.51	0.77
CKB	0.68	0.80	0.89	0.52	0.81
A panel of three proteins	0.92	0.91	0.92	0.83	0.96