Table VI. Cell cycle distribution of 16HBE with knockdown of GSTP1 and controls after repeated treatment with 1 μm B[a]P for 16 weeks. * p < 0.05 vs. 16HBE/pLKO.1+ B[a]P or 16HBE+ B[a]P by t-test. Cell cycle distribution of the cells exposed to vehicle (DMSO) for 16 weeks is also shown and used as controls.

Cell lines	Number of cell (%)
	G0/G1	S	G2/M
16HBE+DMSO	76.10 ± 6.29	12.18 ± 3.15	11.72 ± 3.33
16HBE/pLKO.1+DMSO	75.56 ± 3.72	12.47 ± 2.17	11.97 ± 2.13
16HBE/pLKO.1-GSTP1-shRNA+ DMSO	73.74 ± 2.08	13.46 ± 2.08	12.79 ± 1.87
16HBE+ B[a]P	71.88 ± 2.99	15.10 ± 3.38	13.01 ± 2.76
16HBE/pLKO.1+ B[a]P	71.38 ± 5.77	15.44 ± 3.63	13.18 ± 2.20
16HBE/pLKO.1-GSTP1-shRNA+ B[a]P	54.67 ± 5.24*	29.75 ± 5.25*	15.58 ± 1.35