Table III. Major proteins detected in the Symbiodinium-enriched fraction of Stylophora pistillata related to coral bleaching: apoptosis, vesicle transport, and endo/exocytosis.

Protein accession numbers	Protein function	Protein description
O04093	Apoptosis	Putative inactive disease susceptibility protein LOV1
O42354a	Negative regulation of apoptosis	E3 ubiquitin-protein ligase Mdm2
O60125	Apoptosis	BAG family molecular chaperone regulator 1A
O64789	Apoptosis	Probable disease resistance protein
O92529	Apoptosis	Genome polyprotein
P58801a	Positive regulation of apoptosis	Receptor-interacting serine/threonine-protein kinase 2
Q12933a	Regulation of apoptosis	TNF receptor-associated factor 2
Q32NG6	Induction of apoptosis	Tumor necrosis factor receptor type 1-associated DEATH domain protein
Q6UXS9a	Apoptosis	Inactive caspase-12
Q6ZNE5	Positive regulation of autophagy	Beclin 1-associated autophagy-related key regulator
Q8RXS5	Apoptosis	Probable disease resistance protein At5g63020
Q8W3K3	Apoptosis	Putative disease resistance protein At1g58400
Q8YTC2a	Apoptosis	Uncharacterized WD repeat-containing protein Alr2800
Q95KV0a	IκB kinase activity	Inhibitor of nuclear factor κB kinase subunit β
Q99KF0	Regulation of apoptosis	Caspase recruitment domain-containing protein 14
Q9BZR8	Regulation of apoptosis	Apoptosis facilitator Bcl-2-like protein 14
Q9FL92	Apoptosis	Probable WRKY transcription factor 16
Q9LVT1	Apoptosis	Putative disease resistance protein At5g47280
Q9QAX1	Apoptosis	Genome polyprotein
Q9SZA7	Apoptosis	Probable disease resistance protein At4g33300
Q86VP1a	Inhibits TNF-induced apoptosis	Tax1-binding protein 1
Q3UHC7a	Inhibits CHUK-NF-κB signaling	Disabled homolog 2-interacting protein
Q54DK4a	ARF GTPase activator activity	α-Protein kinase 1
Q8H100a	ARF GTPase activator activity	Probable ADP-ribosylation factor GTPase-activating protein AGD8
O14234a	Calcium ion transport	Calcium-channel protein Cch1
Q0VD05	Calcium ion transport	Voltage-dependent calcium channel γ-3 subunit
Q8NC96a	Endocytosis	Adaptin ear-binding coat-associated protein 1
Q9UU81a	Endocytosis	AP-1 complex subunit γ-1
Q2KJ81a	Endocytosis	AP-1 complex subunit μ-1
Q9Y6Q5a	Endocytosis	AP-1 complex subunit μ-2
O00203a	Endocytosis	AP-3 complex subunit β-1
A2RV61a	Endocytosis	GTPase-activating protein and VPS9 domain-containing protein 1
P90761a	Endocytosis	Putative stoned B-like protein
Q681Q7	Endocytosis	Uncharacterized protein At1g03900
Q9Z1C7a	Guanine nucleotide exchange factor	Rap guanine nucleotide exchange factor 4
Q8C0Q9a	Guanine nucleotide exchange factor	Rap guanine nucleotide exchange factor 5
Q06836	Nucleotide exchange from the GDP- to the GTP-bound form	Arf guanine nucleotide exchange factor SYT1
P47102	Nucleotide exchange from the GDP- to the GTP-bound form	ARF guanine-nucleotide exchange factor 1
Q8NEV8	Rab effector protein in vesicle trafficking	Exophilin-5
Q8R3D1a	Rab GTPase activator activity	TBC1 domain family member 13
Q8BYJ6a	Rab GTPase activator activity	TBC1 domain family member 4
O95759a	Rab GTPase activator activity	TBC1 domain family member 8
Q0IIM8a	Rab GTPase activator activity	TBC1 domain family member 8B
Q3UYK3a	Rab GTPase activator activity	TBC1 domain family member 9
P47709a	Rab GTPase binding	Rabphilin-3A
Q9EQZ7a	Rab GTPase binding	Regulating synaptic membrane exocytosis protein 2
Q9QXG2a	Rab-protein activation	Rab proteins geranylgeranyltransferase component A1
Q8MLZ5	Regulation of small GTPase mediated signal transduction	Ras GTPase-activating protein Gap-2
Q9UJF2a	Regulation of small GTPase mediated signal transduction	Ras GTPase-activating protein nGAP
Q3T000a	v-SNARE	Synaptobrevin homolog YKT6
Q9R0N5a	v-SNARE	Synaptotagmin-5
Q8TDW5a	v-SNARE	Synaptotagmin-like protein 5
Q8N4C7	t-SNARE	Syntaxin-19
Q39233	t-SNARE	Syntaxin-21
Q94KK7	t-SNARE	Syntaxin-52
Q9Y2D4a	Vesicle docking involved in exocytosis	Exocyst complex component 6B
Q9LXX6	Vesicle docking involved in exocytosis	Probable exocyst complex component 6

^a Proteins also detected in coral genome sequences.