Figure 1.

a) 3D-160 MR image of a subcutaneous GOT1 tumour positioned in the neck of the mouse. The tumour is visible as the hyper-intense region central to the image, marked by the 1 cm vertical bar. b) The global segmentation threshold is applied and regions of failed segmentation appear outside the tumour. c) The manual delineation excludes the areas of failed segmentation, and the final result is shown in d) where white pixels represent the region that will be accounted for as tumour volume.