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. 2012 Sep;140(3):307–324. doi: 10.1085/jgp.201210826

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© 2012 Garg et al.

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Figure 4. — Y464A hEAG1 channels exhibit enhanced inactivation. (A) Voltage-pulse protocol and corresponding Y464A hEAG1 currents. (B) Test-pulse currents (during time indicated by a solid bar in A) are shown on an expanded time scale. Test currents elicited after V_pre of −130, −85, −70, and −40 mV are labeled. A fast inactivating component of current is evident when V_pre ≥ −70 mV.