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Superposed structures of X-ray and modeled structures of the selected proteases of the PA clan. Structures of the protozoan (Plasmodium falciparum, magenta), archaeon (Pyrococcus furiosus, cyan), fungus (Neurospora crassa, purple) and plant (Arabidopsis thaliana, fuchsia pink) PA proteases were superposed with the human x-ray structure (1SGI, Homo sapiens, orange). The catalytic triad residues (His, Asp, Ser) are shown in ball and stick models.
