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(A) Phosphorylation status of Src kinase and ABL in leukemia cells with silenced LMW-PTP. (B) The ratio between p-Brc-Abl(210 kDa)/GAPDH and p-c-Abl (135 kDa)/GAPDH, from K562 and Lucena-1 cells with silenced LMW-PTP (LMW-PTP siRNA) or not (scramble siRNA) were quantified by densitometry and plot in the graph. *** p<0.001- significant differences relative to the respective scramble siRNA.
