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. 2012 Sep 5;7(9):e44478. doi: 10.1371/journal.pone.0044478

Table 5. Association with CYP2E1 DraI polymorphism and progression of gastric cancer.

Total TT TA AA
No. No. % No. % No. %
Tumor stage
I 41 25 61.0 12 29.3 4 9.7
II 181 122 67.4 38 21.0 21 11.6
III 162 98 60.5 52 32.1 12 7.4
IV 25 15 60.0 7 28 3 12.0
Adjusteda OR (95% CI)
III vs. I 1.00 1.00 (0.45–2.20) 0.90 (0.25–3.17)
III+ IV vs. I 1.00 0.98 (0.45–2.14) 0.93 (0.28–3.11)
III+ IV vs. I+ II 1.00 1.37 (0.86–2.19) 0.75 (0.37–1.52)
Tumor grade
Low 56 39 69.6 11 19.7 6 10.7
Intermediate 116 75 64.7 31 26.7 10 8.6
High 231 171 74.0 34 14.7 26 11.3
Adjusteda OR (95% CI)
Intermediate vs. Low 1.00 1.39 (0.62–3.09) 1.02 (0.33–3.12)
High vs. Low 1.00 0.71 (0.33–1.54) 1.08 (0.41–2.81)
a

Adjusted for sex, age and smoking habit.