Table 5. Association with CYP2E1 DraI polymorphism and progression of gastric cancer.
Total | TT | TA | AA | ||||
No. | No. | % | No. | % | No. | % | |
Tumor stage | |||||||
I | 41 | 25 | 61.0 | 12 | 29.3 | 4 | 9.7 |
II | 181 | 122 | 67.4 | 38 | 21.0 | 21 | 11.6 |
III | 162 | 98 | 60.5 | 52 | 32.1 | 12 | 7.4 |
IV | 25 | 15 | 60.0 | 7 | 28 | 3 | 12.0 |
Adjusteda OR (95% CI) | |||||||
III vs. I | 1.00 | 1.00 (0.45–2.20) | 0.90 (0.25–3.17) | ||||
III+ IV vs. I | 1.00 | 0.98 (0.45–2.14) | 0.93 (0.28–3.11) | ||||
III+ IV vs. I+ II | 1.00 | 1.37 (0.86–2.19) | 0.75 (0.37–1.52) | ||||
Tumor grade | |||||||
Low | 56 | 39 | 69.6 | 11 | 19.7 | 6 | 10.7 |
Intermediate | 116 | 75 | 64.7 | 31 | 26.7 | 10 | 8.6 |
High | 231 | 171 | 74.0 | 34 | 14.7 | 26 | 11.3 |
Adjusteda OR (95% CI) | |||||||
Intermediate vs. Low | 1.00 | 1.39 (0.62–3.09) | 1.02 (0.33–3.12) | ||||
High vs. Low | 1.00 | 0.71 (0.33–1.54) | 1.08 (0.41–2.81) |
Adjusted for sex, age and smoking habit.