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. 2012 Sep 5;7(9):e42450. doi: 10.1371/journal.pone.0042450

Figure 1. SNPs of the CRH-R1 gene examined in this study.

Figure 1

CRH-R1 is located on chromosome 17q21.31. SNPs of rs7209436, rs242924, and rs110402 are covering the gene in first and second intron on 5′ end including promoter region, a total region of 51.55 kb that has links with haplotype block. The structure was determined using the confidence interval method in Haploview such that we were able to estimate haplotypes for every participant with a posterior probability of >0.998. These SNPs had a minor allele frequency of >1.0% in the Japanese population.