Table 2. Pooled seroprevalence of chronic hepatitis B infection by immigrant class and region of origin.
Number of Studies | Number of Subjects | Pooled HBsAg Seroprevalence Percent (95% CI) | I 2 (%) | ||
Overall Seroprevalence | Overall | 110 | 209,822 | 7.2 (6.3 to 8.2) | 98.1 |
Immigrants | 50 | 72,510 | 5.1 (4.0 to 6.4) | 97.0 | |
Refugees | 57 | 134,418 | 9.6 (8.2 to 11.1) | 98.1 | |
Mixed | 3 | 2,894 | 7.7 (6.7 to 8.7) | 0 | |
East Asia & The Pacific | Overall | 40 | 62,258 | 11.3 (10.3 to 12.4) | 89.1 |
Immigrants | 16 | 8,550 | 8.6 (6.7 to 10.9) | 89.2 | |
Refugees | 23 | 53,381 | 13.2 (12.0 to 14.4) | 85.8 | |
Mixed | 1 | 327 | 8.6 (6.0 to 12.1) | 0 | |
Sub-Saharan Africa | Overall | 33 | 22,219 | 10.3 (9.1 to 11.8) | 86.2 |
Immigrants | 12 | 4,581 | 9.9 (7.1 to 13.7) | 90.3 | |
Refugees | 19 | 16,022 | 10.5 (9.0 to 12.2) | 84.3 | |
Mixed | 2 | 1,616 | 10.7 (8.1 to 13.9) | 65.5 | |
Eastern Europe & Central Asia | Overall | 37 | 31,549 | 5.8 (4.3 to 7.9) | 96.8 |
Immigrants | 13 | 14,301 | 5.9 (4.1 to 8.5) | 93.4 | |
Refugees | 22 | 17,169 | 5.9 (3.7 to 9.1) | 97.5 | |
Mixed | 2 | 79 | 6.6 (0.8 to 37.2) | 63.5 | |
South Asia | Overall | 11 | 1,567 | 4.6 (2.6 to 7.8) | 71.5 |
Immigrants | 4 | 441 | 2.4 (0.3 to 15.4) | 73.3 | |
Refugees | 5 | 845 | 6.5 (3.8 to 11.1) | 71.9 | |
Mixed | 2 | 281 | 2.0 (0.9 to 4.5) | 0 | |
Middle East & North Africa | Overall | 17 | 19,127 | 2.0 (1.6 to 2.9) | 79.0 |
Immigrants | 8 | 12,541 | 1.8 (1.3 to 2.7) | 79.8 | |
Refugees | 7 | 6,470 | 2.6 (1.3 to 4.9) | 84.7 | |
Mixed | 2 | 116 | 3.6 (1.4 to 9.2) | 0 | |
Latin America & Caribbean | Overall | 18 | 29,554 | 1.7 (1.1 to 2.7) | 86.1 |
Immigrants | 9 | 9,539 | 1.4 (0.8 to 2.7) | 77.2 | |
Refugees | 7 | 19,580 | 3.1 (0.8 to 11.6) | 92.3 | |
Mixed | 2 | 435 | 0.6 (0.2 to 2.0) | 0 |
The total number of subjects for each specific region exceeds those reported in Appendix Table 3 because they include available data from studies that included mixed populations in terms of region of origin. Proportions were logit transformed prior to pooling with a random-effects model. HBsAg = hepatitis B surface antigen. CI = confidence interval.