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. 2012 Sep 5;7(9):e44611. doi: 10.1371/journal.pone.0044611

Table 2. Pooled seroprevalence of chronic hepatitis B infection by immigrant class and region of origin.

Number of Studies Number of Subjects Pooled HBsAg Seroprevalence Percent (95% CI) I 2 (%)
Overall Seroprevalence Overall 110 209,822 7.2 (6.3 to 8.2) 98.1
Immigrants 50 72,510 5.1 (4.0 to 6.4) 97.0
Refugees 57 134,418 9.6 (8.2 to 11.1) 98.1
Mixed 3 2,894 7.7 (6.7 to 8.7) 0
East Asia & The Pacific Overall 40 62,258 11.3 (10.3 to 12.4) 89.1
Immigrants 16 8,550 8.6 (6.7 to 10.9) 89.2
Refugees 23 53,381 13.2 (12.0 to 14.4) 85.8
Mixed 1 327 8.6 (6.0 to 12.1) 0
Sub-Saharan Africa Overall 33 22,219 10.3 (9.1 to 11.8) 86.2
Immigrants 12 4,581 9.9 (7.1 to 13.7) 90.3
Refugees 19 16,022 10.5 (9.0 to 12.2) 84.3
Mixed 2 1,616 10.7 (8.1 to 13.9) 65.5
Eastern Europe & Central Asia Overall 37 31,549 5.8 (4.3 to 7.9) 96.8
Immigrants 13 14,301 5.9 (4.1 to 8.5) 93.4
Refugees 22 17,169 5.9 (3.7 to 9.1) 97.5
Mixed 2 79 6.6 (0.8 to 37.2) 63.5
South Asia Overall 11 1,567 4.6 (2.6 to 7.8) 71.5
Immigrants 4 441 2.4 (0.3 to 15.4) 73.3
Refugees 5 845 6.5 (3.8 to 11.1) 71.9
Mixed 2 281 2.0 (0.9 to 4.5) 0
Middle East & North Africa Overall 17 19,127 2.0 (1.6 to 2.9) 79.0
Immigrants 8 12,541 1.8 (1.3 to 2.7) 79.8
Refugees 7 6,470 2.6 (1.3 to 4.9) 84.7
Mixed 2 116 3.6 (1.4 to 9.2) 0
Latin America & Caribbean Overall 18 29,554 1.7 (1.1 to 2.7) 86.1
Immigrants 9 9,539 1.4 (0.8 to 2.7) 77.2
Refugees 7 19,580 3.1 (0.8 to 11.6) 92.3
Mixed 2 435 0.6 (0.2 to 2.0) 0

The total number of subjects for each specific region exceeds those reported in Appendix Table 3 because they include available data from studies that included mixed populations in terms of region of origin. Proportions were logit transformed prior to pooling with a random-effects model. HBsAg  =  hepatitis B surface antigen. CI  =  confidence interval.