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. 2012 Sep 5;7(9):e41592. doi: 10.1371/journal.pone.0041592

Figure 5. TCS inhibits MDA-MB-231 xenograft growth in nude mice.

Figure 5

A. Twelve female BALB/c nude mice received an injection of MDA-MB-231 cells and were divided into 2 groups. TCS was administered at a dose of 5.0 mg/kg every other day for a total of 7 injections. On day 16, mice were sacrificed and excised tumors are shown in the right panel. The dose applied had no detectable toxicological effects on nude mice, such as changes in body weight. B. A representative comparison between a TCS-treated mouse and a PBS-treated control mouse. C. TCS significantly reduced tumor volume from the 6th day of treatment onward. D. The mean tumor weight in TCS group was smaller than that of control. For asterisks in C and D, p<0.05.