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. 2012 Sep 5;7(9):e44190. doi: 10.1371/journal.pone.0044190

Figure 9. Reducing responses by adding rigidity to the C1–C9 moiety.

Figure 9

(A) Current responses elicited by (10E,12Z)-hexadecadien-4-yn-1-ol (10), (4Z,10E,12Z)-hexadecatrien-1-ol (11), and bombykol (1) from BmorOR1•BmorOrco-expressing oocytes (ligands presented at 10 µM). EC50s 1.7×10−5M, 1.3×10−5M, and 5.9×10−6M, respectively. (B) Dose-dependent relationships, n = 3–4.